Multiple sequence alignment
Multiple sequence alignments are of great interest because homologous sequences, although not necessarily having great similarity, often preserve similar structures and functions.
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Introduction
One of the fundamental questions in biology is to know which proteins are related to another protein.
We can find some examples in this Venn diagram of orthologous sequences; which are similar because they have some common ancestor. Or, for example: cytochrome c (a protein found in mitochondria) from humans and mice.